Cross-border data transfer regulations are critical for maintaining the integrity and security of personal data as it is shared internationally. These regulations ensure that personal data is handled in a manner that respects the privacy rights of individuals and complies with local and international legal standards. Organisations must navigate these complex requirements to avoid legal repercussions, safeguarding their reputation as well as the privacy of the individuals. Following the recent enforcement of the Saudi Personal Data Protection Law (PDPL), this guide provides a comprehensive overview of key regulatory requirements for cross-border data transfers in selected Middle Eastern countries, focusing on personal data protection laws.